HEPBS

HEPBS
Names
	IUPAC name N-(2-Hydroxyethyl)piperazine-N'-(4-butanesulfonic acid)[1][2][3]
	Other names HEPBS
Identifiers
CAS Number	161308-36-7;
3D model (JSmol)	Interactive image;
PubChem CID	9965191;
	InChI InChI=1S/C10H22N2O4S/c13-9-8-12-6-4-11(5-7-12)3-1-2-10-17(14,15)16/h13H,1-10H2,(H,14,15,16) Key: LOJNFONOHINEFI-UHFFFAOYSA-N;
	SMILES C1CN(CCN1CCCCS(=O)(=O)O)CCO;
Properties
Chemical formula	C10H22N2O4S
Molar mass	266.356 g/mol
Appearance	White crystalline powder
Density	1.25 g/cm3 (predicted)
Melting point	211–216 °C (412–421 °F; 484–489 K)
Acidity (pKa)	8.3
Hazards
Main hazards	Irritant
GHS Signal word	Warning
GHS hazard statements	H315, H319, H335
GHS precautionary statements	P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362, P403+233, P405, P501
Flash point	Non-flammable
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	Infobox references

HEPBS (N-(2-Hydroxyethyl)piperazine-N'-(4-butanesulfonic acid)) is a zwitterionic organic chemical buffering agent; one of Good's buffers. HEPBS and HEPES have very similar structures and properties, HEPBS also having an acidity (pK_a) in the physiological range (7.6-9.0 useful range). This makes it possible to use it for cell culture work.

HEPBS ¹H NMR spectrum.

References

"Compound Summary for CID 9965191". PubChem. 2006-10-25.
"HEPBS, 99% (HPLC)". AKSci. 2017-07-23.
"HEPBS (CAS 161308-36-7)". Santa Cruz Biotechnology.

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[1] "Compound Summary for CID 9965191". PubChem. 2006-10-25.

[2] "HEPBS, 99% (HPLC)". AKSci. 2017-07-23.

[3] "HEPBS (CAS 161308-36-7)". Santa Cruz Biotechnology.