Monopolin

Monopolin is a protein complex that in yeast is composed of the four proteins CSM1, HRR25, LRS4, and MAM1. Monopolin is required for the segregation of homologous centromeres to opposite poles of a dividing cell during anaphase I of meiosis.[1]

Monopolin complex subunit CSM1
Identifiers
OrganismS. cerevisiae
SymbolCSM1
Entrez850447
RefSeq (mRNA)NM_001178792
RefSeq (Prot)NP_010009
UniProtP25651
Other data
ChromosomeIII: 0.26 - 0.26 Mb
Casein kinase I homolog HRR25
Identifiers
OrganismS. cerevisiae
SymbolHRR25
Entrez855897
RefSeq (mRNA)NM_001184018
RefSeq (Prot)NP_015120
UniProtP29295
Other data
EC number2.7.11.1
ChromosomeXVI: 0.16 - 0.17 Mb
Monopolin complex subunit LRS4
Identifiers
OrganismS. cerevisiae
SymbolLRS4
Entrez852049
RefSeq (mRNA)NM_001180747
RefSeq (Prot)NP_010727
UniProtQ04087
Other data
ChromosomeIV: 1.34 - 1.34 Mb
Monopolin complex subunit MAM1
Identifiers
OrganismS. cerevisiae
SymbolMAM1
Entrez856843
RefSeq (mRNA)NM_001178997
RefSeq (Prot)NP_011032
UniProtP40065
Other data
ChromosomeV: 0.37 - 0.37 Mb

References
  1. Corbett KD, Yip CK, Ee LS, Walz T, Amon A, Harrison SC (August 2010). "The monopolin complex crosslinks kinetochore components to regulate chromosome-microtubule attachments". Cell. 142 (4): 556–67. doi:10.1016/j.cell.2010.07.017. PMC 2955198. PMID 20723757.


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