Arbaclofen placarbil
Arbaclofen placarbil (/ɑːrˈbækloʊfɛn pləˈkɑːrbɪl/ ar-BAK-loh-fen plə-KAR-bil, also known as XP19986) is a prodrug of R-baclofen. Arbaclofen placarbil possesses more favorable pharmacokinetic profile than baclofen, with less fluctuations in plasma drug levels. It was being developed as a potential treatment for patients with GERD and spasticity due to multiple sclerosis; however, in May 2013 XenoPort announced the termination of development because of unsuccessful results in phase III clinical trials.[1]
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| ECHA InfoCard | 100.221.150  |
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| Formula | C19H26ClNO6 |
| Molar mass | 399.87 g·mol−1 |
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It is being developed as an addiction medicine to treat alcoholism. [2]
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References
- "Archived copy". Archived from the original on 2013-12-02. Retrieved 2013-06-03.CS1 maint: archived copy as title (link)
- "Pill that replaces alcohol aims to end 'glass of wine' craving".
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